Secrets of Batch Process Scale-Up is a course that covers topics such as:
- Scale-Up - An Overview
- Overview of scale-up issues
- Role of the Pilot Plant
- Technology transfer issues
- Process Design for Scale-Up
- Importance of engineering in PDs
- Process development strategies
- Raw Materials
- Large-scale charging methods and issues
- Raw material and route selection
- Batch Reactors
- Characteristics of batch operations
- Typical plant operations and equipment
- Following Reaction Progress
- Sampling methods / issues
- Reaction endpoint determination
- On-line analytical techniques
- Temperature Control
- Heat transfer in batch reactors
- Large scale temperature control
- Controlling exothermic reactions
- Quench & Work-Up
- Phase continuity issues and emulsions
- Liquid-liquid extractions
- Agitation and Mixing
- Mixing limited reaction
- Large scale mixing equipment
- Mixing scale-up / scale-down
- Crystallization and Precipitation
- Controlling supersaturation
- Basic principles / yield estimation
- Scale-up issues
- Distillation & Stripping
- Azeotropes and solvent exchange
- Differential distillation
- Process Hazards and Safety Assessment
- Process hazard assessments and evaluations
- Common hazards in large-scale processing
- Product Isolation and Drying
- Filtration and drying equipment
- Large-scale solid-liquid separations
- Filtration and drying modelling
Secrets of Batch Process Scale-Up will be held in Cambridge, United States on 23-25 Apr 2024.
